Goals from Elias Pelembe and Thulani Hlatshwayo ensured the Clever Boys got off to a flying start in the new season while Lorenzo Gordinho scored the consolation with eight minutes remaining.
It was a sweet victory for the hosts, but bitter pill for Komphela, who despite signing over 10 players continued with a poor spell at the Naturena.
Chippa United edged out Free State Stars 2-1 in a match clash played at the Nelson Mandela Stadium while newboys Baroka FC were held 1-1 by Ajax Cape Town in Polokwane.
Newly formed Cape Town FC fired warning shots beating Polokwane City 2-0 at home in Cape Town.
Wednesday Absa Premiership fixtures
Orlando Pirates V Golden Arrows (Orlando Stadium), Platinum Stars V SuperSport (Royal Bafokeng Stadium), Bloemfontein Celtic V Maritzburg (DR Molemela Stadium)
All matches Kick-Off at 19:30pm